April 12, 2006

In recent weeks, there have been several reports of fungal keratitis among contact lens wearers in certain Asian nations and in the U.S. To our knowledge, none of these reported infections have been attributed to any AMO products. In light of the heightened interest in this issue, however, AMO has reviewed the data concerning our COMPLETE® multi-purpose solutions and reaffirmed the safety of these products. This affirmation is based on the stringent pre-market testing required for our products, the rigorous quality system under which they are designed and manufactured and the global safety history of the products. We carefully monitor all reports of adverse events. This product has an excellent safety record. We continue to stand behind our contact lens disinfecting systems, including COMPLETE® multi-purpose solutions and Ultracare® disinfecting peroxide systems.

We consider any lens-related infection to be serious and remind all contact lens wearers of the following important cleaning guidelines:

• Wash and dry hands before putting on or removing lenses
• Always clean your contact lens case by rinsing it with COMPLETE® solution and allowing it to air dry
• Do not wear lenses beyond the recommended period
• Never reuse solution
• Do not touch the tip of the solution bottle to any surface
• Remove and stop using lenses if you experience unusual eye symptoms; seek medical consultation if necessary